טוען...

Inhibition of Protein Interactions: Co-Crystalized Protein-Protein Interfaces are Nearly as Good as Holo Proteins in Rigid-Body Ligand Docking

Modulating protein interaction pathways may lead to the cure of many diseases. Known protein-protein inhibitors bind to large pockets on the protein-protein interface. Such large pockets are detected also in the protein-protein complexes without known inhibitors, making such complexes potentially dr...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Comput Aided Mol Des
Main Authors: Belkin, Saveliy, Kundrotas, Petras J., Vakser, Ilya A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640133/
https://ncbi.nlm.nih.gov/pubmed/30003468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-018-0124-z
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!