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BMP4 mutations in tooth agenesis and low bone mass

OBJECTIVE: To identify an uncommon genetic cause of tooth agenesis (TA) by utilizing whole exome sequencing (WES) and targeted Sanger sequencing in a cohort of 120 patients with isolated TA. DESIGN: One deleterious mutation in the gene encoding bone morphogenetic protein 4 (BMP4) was identified in 6...

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Detalles Bibliográficos
Publicado en:Arch Oral Biol
Main Authors: Yu, Miao, Wang, Hao, Fan, Zhuangzhuang, Xie, Chencheng, Liu, Haochen, Liu, Yang, Han, Dong, Wong, Sing-Wai, Feng, Hailan
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639811/
https://ncbi.nlm.nih.gov/pubmed/31128441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.archoralbio.2019.05.012
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