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Activation of Necroptosis by Engineered Self Tumor-Derived Exosomes Loaded with CRISPR/Cas9

CRISPR/Cas9 has proved its efficiency in vitro, where we now know that this tool can efficiently target specific parts of the genome. These modifications can be used to generate advanced models of human diseases, address specific functions of genes, and develop new therapeutic strategies. Even if th...

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Detalles Bibliográficos
Publicado en:Mol Ther Nucleic Acids
Autores principales: Gulei, Diana, Berindan-Neagoe, Ioana
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639591/
https://ncbi.nlm.nih.gov/pubmed/31323464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.05.032
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