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In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation

The GTPases of the Ras superfamily regulate cell growth, membrane traffic and the cytoskeleton, and a wide range of diseases are caused by mutations in particular members. They function as switchable landmarks with the active GTP-bound form recruiting to the membrane a specific set of effector prote...

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Veröffentlicht in:eLife
Hauptverfasser: Gillingham, Alison K, Bertram, Jessie, Begum, Farida, Munro, Sean
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639074/
https://ncbi.nlm.nih.gov/pubmed/31294692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45916
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