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HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon

The bacterial Sec translocon is a multi-protein complex responsible for translocating diverse proteins across the plasma membrane. For post-translational protein translocation, the Sec-channel – SecYEG – associates with the motor protein SecA to mediate the ATP-dependent transport of pre-proteins ac...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ahdash, Zainab, Pyle, Euan, Allen, William John, Corey, Robin A, Collinson, Ian, Politis, Argyris
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639072/
https://ncbi.nlm.nih.gov/pubmed/31290743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47402
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