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ATP-induced asymmetric pre-protein folding as a driver of protein translocation through the Sec machinery
Transport of proteins across membranes is a fundamental process, achieved in every cell by the ‘Sec’ translocon. In prokaryotes, SecYEG associates with the motor ATPase SecA to carry out translocation for pre-protein secretion. Previously, we proposed a Brownian ratchet model for transport, whereby...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6335059/ https://ncbi.nlm.nih.gov/pubmed/30601115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41803 |
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