Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen

Hsp90 is a conserved molecular chaperone that assists in the folding and function of diverse cellular regulators, with a profound impact on biology, disease, and evolution. As a central hub of protein interaction networks, Hsp90 engages with hundreds of protein–protein interactions within eukaryotic...

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Détails bibliographiques
Publié dans:PLoS Biol
Auteurs principaux: O’Meara, Teresa R., O’Meara, Matthew J., Polvi, Elizabeth J., Pourhaghighi, M. Reza, Liston, Sean D., Lin, Zhen-Yuan, Veri, Amanda O., Emili, Andrew, Gingras, Anne-Claude, Cowen, Leah E.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6638986/
https://ncbi.nlm.nih.gov/pubmed/31283755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000358
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