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Quick assessment for systematic test statistic inflation/deflation due to null model misspecifications in genome-wide environment interaction studies
Gene-environment (GxE) interaction is one potential explanation for the missing heritability problem. A popular approach to genome-wide environment interaction studies (GWEIS) is based on regression models involving interactions between genetic variants and environment variables. Unfortunately, GWEI...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6638962/ https://ncbi.nlm.nih.gov/pubmed/31318927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219825 |
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