Gas6/Axl signaling attenuates alveolar inflammation in ischemia-reperfusion-induced acute lung injury by up-regulating SOCS3-mediated pathway

BACKGROUND: Axl is a cell surface receptor tyrosine kinase, and activation of the Axl attenuates inflammation induced by various stimuli. Growth arrest-specific 6 (Gas6) has high affinity for Axl receptor. The role of Gas6/Axl signaling in ischemia-reperfusion-induced acute lung injury (IR-ALI) has...

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Publicat a:PLoS One
Autors principals: Peng, Chung-Kan, Wu, Chin-Pyng, Lin, Jr-Yu, Peng, Shih-Chi, Lee, Chien-Hsing, Huang, Kun-Lun, Shen, Chih-Hao
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6638944/
https://ncbi.nlm.nih.gov/pubmed/31318922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219788
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