Determining the Relationship Between Hot Flushes and LH Pulses in Menopausal Women Using Mathematical Modeling

BACKGROUND: Hypothalamic kisspeptin/neurokinin B/dynorphin (KNDy) neurones regulate LH pulsatility. It is widely accepted that the menopausal hot flush (HF) consistently synchronizes with the LH pulse, implicating the hypothalamic KNDy neurones in generating LH pulsatility and HF. Using a modern imm...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Prague, Julia K, Voliotis, Margaritis, Clarke, Sophie, Comninos, Alexander N, Abbara, Ali, Jayasena, Channa N, Roberts, Rachel E, Yang, Lisa, Veldhuis, Johannes D, Tsaneva-Atanasova, Krasimira, McArdle, Craig A, Dhillo, Waljit S
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637789/
https://ncbi.nlm.nih.gov/pubmed/30985867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-02797
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