Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial

BACKGROUND: Hot flushes affect 70% of menopausal women and often severely impact physical, psychosocial, sexual, and overall wellbeing. Hormone replacement therapy is effective but is not without risk. Neurokinin B signalling is increased in menopausal women, and has been implicated as an important...

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發表在:Lancet
Main Authors: Prague, Julia K, Roberts, Rachel E, Comninos, Alexander N, Clarke, Sophie, Jayasena, Channa N, Nash, Zachary, Doyle, Chedie, Papadopoulou, Deborah A, Bloom, Stephen R, Mohideen, Pharis, Panay, Nicholas, Hunter, Myra S, Veldhuis, Johannes D, Webber, Lorraine C, Huson, Les, Dhillo, Waljit S
格式: Artigo
語言:Inglês
出版: Elsevier 2017
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439024/
https://ncbi.nlm.nih.gov/pubmed/28385352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(17)30823-1
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