Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial

BACKGROUND: Hot flushes affect 70% of menopausal women and often severely impact physical, psychosocial, sexual, and overall wellbeing. Hormone replacement therapy is effective but is not without risk. Neurokinin B signalling is increased in menopausal women, and has been implicated as an important...

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Detaylı Bibliyografya
Yayımlandı:Lancet
Asıl Yazarlar: Prague, Julia K, Roberts, Rachel E, Comninos, Alexander N, Clarke, Sophie, Jayasena, Channa N, Nash, Zachary, Doyle, Chedie, Papadopoulou, Deborah A, Bloom, Stephen R, Mohideen, Pharis, Panay, Nicholas, Hunter, Myra S, Veldhuis, Johannes D, Webber, Lorraine C, Huson, Les, Dhillo, Waljit S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2017
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439024/
https://ncbi.nlm.nih.gov/pubmed/28385352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(17)30823-1
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