Routine Cerebrospinal Fluid Cytology Reveals Unique Inclusions in Macrophages During Treatment With Nusinersen

Background: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disorder characterized by degeneration of spinal motor neurons leading to muscular weakness. The antisense oligonucleotide nusinersen was approved for the treatment of patients with 5q-associated SMA. Treatment mus...

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Udgivet i:Front Neurol
Main Authors: Gingele, Stefan, Hümmert, Martin W., Alvermann, Sascha, Jendretzky, Konstantin F., Bönig, Lena, Brieskorn, Marina, Schwenkenbecher, Philipp, Sühs, Kurt-Wolfram, Müschen, Lars H., Osmanovic, Alma, Schreiber-Katz, Olivia, Stangel, Martin, Petri, Susanne, Skripuletz, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neurology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637748/
https://ncbi.nlm.nih.gov/pubmed/31354609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.00735
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