Routine Cerebrospinal Fluid Cytology Reveals Unique Inclusions in Macrophages During Treatment With Nusinersen

Background: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disorder characterized by degeneration of spinal motor neurons leading to muscular weakness. The antisense oligonucleotide nusinersen was approved for the treatment of patients with 5q-associated SMA. Treatment mus...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Gingele, Stefan, Hümmert, Martin W., Alvermann, Sascha, Jendretzky, Konstantin F., Bönig, Lena, Brieskorn, Marina, Schwenkenbecher, Philipp, Sühs, Kurt-Wolfram, Müschen, Lars H., Osmanovic, Alma, Schreiber-Katz, Olivia, Stangel, Martin, Petri, Susanne, Skripuletz, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637748/
https://ncbi.nlm.nih.gov/pubmed/31354609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.00735
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