Routine Cerebrospinal Fluid Cytology Reveals Unique Inclusions in Macrophages During Treatment With Nusinersen

Background: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disorder characterized by degeneration of spinal motor neurons leading to muscular weakness. The antisense oligonucleotide nusinersen was approved for the treatment of patients with 5q-associated SMA. Treatment mus...

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Dades bibliogràfiques
Publicat a:Front Neurol
Autors principals: Gingele, Stefan, Hümmert, Martin W., Alvermann, Sascha, Jendretzky, Konstantin F., Bönig, Lena, Brieskorn, Marina, Schwenkenbecher, Philipp, Sühs, Kurt-Wolfram, Müschen, Lars H., Osmanovic, Alma, Schreiber-Katz, Olivia, Stangel, Martin, Petri, Susanne, Skripuletz, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Neurology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637748/
https://ncbi.nlm.nih.gov/pubmed/31354609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.00735
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