A Cationic Tetraphenylethene as a Light-Up Supramolecular Probe for DNA G-Quadruplexes

Guanine-quadruplexes (G4s) are targets for anticancer therapeutics. In this context, human telomeric DNA (HT-DNA) that can fold into G4s sequences are of particular interest, and their stabilization with small molecules through a visualizable process has become a challenge. As a new type of ligand f...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Kotras, Clément, Fossépré, Mathieu, Roger, Maxime, Gervais, Virginie, Richeter, Sébastien, Gerbier, Philippe, Ulrich, Sébastien, Surin, Mathieu, Clément, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637260/
https://ncbi.nlm.nih.gov/pubmed/31355185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00493
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