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Probing the Limits of Supramolecular G-Quadruplexes Using Atomistic Molecular Dynamics Simulations

Guanosine and related derivatives self-assemble in the presence of cations like potassium into supramolecular G-quadruplexes (SGQs), where four guanine moieties form planar tetrads (T) that coaxially stack into columnar aggregates with broad size distributions. However, SGQs made from 8-aryl-2’-deox...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Inorganica Chim Acta
Prif Awduron: García-Arriaga, Marilyn, Acosta-Santiago, Maxier, Cruz, Antony, Rivera-Rivera, José M., López, Gustavo E., Rivera, José M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649357/
https://ncbi.nlm.nih.gov/pubmed/29062143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ica.2017.08.051
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