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Improved detection of common variants in coronary artery disease and blood pressure using a pleiotropy cFDR method

Plenty of genome-wide association studies (GWASs) have identified numerous single nucleotide polymorphisms (SNPs) for coronary artery disease (CAD) and blood pressure (BP). However, these SNPs only explain a small proportion of the heritability of two traits/diseases. Although high BP is a major ris...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mao, Xiang-Jie, Zhang, Qiang, Xu, Fei, Gao, Pan, Sun, Nan, Wang, Bo, Tang, Qi-Xin, Hao, Yi-Bin, Sun, Chang-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637206/
https://ncbi.nlm.nih.gov/pubmed/31316127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46808-2
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