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High-throughput stability screening for detergent-solubilized membrane proteins

Protein stability in detergent or membrane-like environments is the bottleneck for structural studies on integral membrane proteins (IMP). Irrespective of the method to study the structure of an IMP, detergent solubilization from the membrane is usually the first step in the workflow. Here, we estab...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Kotov, Vadim, Bartels, Kim, Veith, Katharina, Josts, Inokentijs, Subhramanyam, Udaya K. Tiruttani, Günther, Christian, Labahn, Jörg, Marlovits, Thomas C., Moraes, Isabel, Tidow, Henning, Löw, Christian, Garcia-Alai, Maria M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637136/
https://ncbi.nlm.nih.gov/pubmed/31316088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46686-8
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