More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction

Our understanding of how capillary blood flow and oxygen distribute across cortical layers to meet the local metabolic demand is incomplete. We addressed this question by using two-photon imaging of resting-state microvascular oxygen partial pressure (PO(2)) and flow in the whisker barrel cortex in...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Li, Baoqiang, Esipova, Tatiana V, Sencan, Ikbal, Kılıç, Kıvılcım, Fu, Buyin, Desjardins, Michele, Moeini, Mohammad, Kura, Sreekanth, Yaseen, Mohammad A, Lesage, Frederic, Østergaard, Leif, Devor, Anna, Boas, David A, Vinogradov, Sergei A, Sakadžić, Sava
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2019
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636997/
https://ncbi.nlm.nih.gov/pubmed/31305237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42299
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