More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction

Our understanding of how capillary blood flow and oxygen distribute across cortical layers to meet the local metabolic demand is incomplete. We addressed this question by using two-photon imaging of resting-state microvascular oxygen partial pressure (PO(2)) and flow in the whisker barrel cortex in...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Li, Baoqiang, Esipova, Tatiana V, Sencan, Ikbal, Kılıç, Kıvılcım, Fu, Buyin, Desjardins, Michele, Moeini, Mohammad, Kura, Sreekanth, Yaseen, Mohammad A, Lesage, Frederic, Østergaard, Leif, Devor, Anna, Boas, David A, Vinogradov, Sergei A, Sakadžić, Sava
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636997/
https://ncbi.nlm.nih.gov/pubmed/31305237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42299
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