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Atherosclerosis is associated with a decrease in cerebral microvascular blood flow and tissue oxygenation

Chronic atherosclerosis may cause cerebral hypoperfusion and inadequate brain oxygenation, contributing to the progression of cognitive decline. In this study, we exploited two-photon phosphorescence lifetime microscopy to measure the absolute partial pressure of oxygen (PO(2)) in cortical tissue in...

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Veröffentlicht in:PLoS One
Hauptverfasser: Li, Baoqiang, Lu, Xuecong, Moeini, Mohammad, Sakadžić, Sava, Thorin, Eric, Lesage, Frederic
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716780/
https://ncbi.nlm.nih.gov/pubmed/31469849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221547
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