Anti-angiogenic effect of a humanized antibody blocking the Wnt/β-catenin signaling pathway

PURPOSE: Our previous study demonstrated that Mab2F1, a murine monoclonal antibody blocking the Wnt/β-catenin signaling pathway, has beneficial effects on experimental diabetic retinopathy and choroidal neovascularization (NV). The aforementioned antibody has been humanized. This study evaluated eff...

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Bibliografiset tiedot
Julkaisussa:Microvasc Res
Päätekijät: Qiu, Fangfang, Shin, Younghwa, Chen, Danyang, Cheng, Rui, Chen, Qian, Zhou, Kelu, Larrick, James W., Mendelson, Andrew R., Ma, Jian-xing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636822/
https://ncbi.nlm.nih.gov/pubmed/29630973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2018.03.011
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