Immunoproteomic analysis of a Chikungunya poxvirus-based vaccine reveals high HLA class II immunoprevalence

BACKGROUND: Efficient adaptive antiviral cellular and humoral immune responses require previous recognition of viral antigenic peptides bound to human leukocyte antigen (HLA) class I and II molecules, which are exposed on the surface of infected and antigen presenting cells, respectively. The HLA-re...

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Détails bibliographiques
Publié dans:PLoS Negl Trop Dis
Auteurs principaux: Lorente, Elena, Barriga, Alejandro, Barnea, Eilon, Palomo, Concepción, García-Arriaza, Juan, Mir, Carmen, Esteban, Mariano, Admon, Arie, López, Daniel
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636782/
https://ncbi.nlm.nih.gov/pubmed/31276466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007547
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