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Diversity of Natural Self-Derived Ligands Presented by Different HLA Class I Molecules in Transporter Antigen Processing-Deficient Cells
The transporter associated with antigen processing (TAP) translocates the cytosol-derived proteolytic peptides to the endoplasmic reticulum lumen where they complex with nascent human leukocyte antigen (HLA) class I molecules. Non-functional TAP complexes and viral or tumoral blocking of these trans...
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Главные авторы: | , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Public Library of Science
2013
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3608615/ https://ncbi.nlm.nih.gov/pubmed/23555621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059118 |
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