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ATP-dependent helicase activity is dispensable for the physiological functions of Recql4

Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive disorder characterized by skin rash (poikiloderma), skeletal dysplasia, small stature, juvenile cataracts, sparse or absent hair, and predisposition to specific malignancies such as osteosarcoma and hematological neoplasms. RTS is caused...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Castillo-Tandazo, Wilson, Smeets, Monique F., Murphy, Vincent, Liu, Rui, Hodson, Charlotte, Heierhorst, Jörg, Deans, Andrew J., Walkley, Carl R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636780/
https://ncbi.nlm.nih.gov/pubmed/31276497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008266
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