Repurposed Antimicrobial Combination Therapy: Tobramycin-Ciprofloxacin Hybrid Augments Activity of the Anticancer Drug Mitomycin C Against Multidrug-Resistant Gram-Negative Bacteria

The lack of therapeutic options to treat infections caused by multidrug-resistant (MDR) pathogens, especially Gram-negative bacteria, is apparent. Therefore, it is imperative to develop new strategies to address the problem of antimicrobial resistance. Repurposing non-antibiotic commercial drugs for...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Domalaon, Ronald, Ammeter, Derek, Brizuela, Marc, Gorityala, Bala Kishan, Zhanel, George G., Schweizer, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636613/
https://ncbi.nlm.nih.gov/pubmed/31354660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01556
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