Mutagenesis Induced by Sub-Lethal Doses of Ciprofloxacin: Genotypic and Phenotypic Differences Between the Pseudomonas aeruginosa Strain PA14 and Clinical Isolates

Bacterial resistance is a severe threat to global public health. Exposure to sub-lethal concentrations has been considered a major driver of mutagenesis leading to antibiotic resistance in clinical settings. Ciprofloxacin is broadly used to treat infections caused by Pseudomonas aeruginosa, whereas...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Autores principales: Migliorini, Letícia Busato, Brüggemann, Holger, de Sales, Romario Oliveira, Koga, Paula Célia Mariko, de Souza, Andrea Vieira, Martino, Marines Dalla Valle, Galhardo, Rodrigo S., Severino, Patricia
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636244/
https://ncbi.nlm.nih.gov/pubmed/31354657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01553
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