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Extensions of ℓ(1) regularization increase detection specificity for cell-type specific parameters in dynamic models
BACKGROUND: Ordinary differential equation systems are frequently utilized to model biological systems and to infer knowledge about underlying properties. For instance, the development of drugs requires the knowledge to which extent malign cells differ from healthy ones to provide a specific treatme...
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| Pubblicato in: | BMC Bioinformatics |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6636101/ https://ncbi.nlm.nih.gov/pubmed/31311516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2976-1 |
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