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Extensions of ℓ(1) regularization increase detection specificity for cell-type specific parameters in dynamic models

BACKGROUND: Ordinary differential equation systems are frequently utilized to model biological systems and to infer knowledge about underlying properties. For instance, the development of drugs requires the knowledge to which extent malign cells differ from healthy ones to provide a specific treatme...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Bioinformatics
Egile Nagusiak: Dolejsch, Pascal, Hass, Helge, Timmer, Jens
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636101/
https://ncbi.nlm.nih.gov/pubmed/31311516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2976-1
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