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Disruption of nuclear speckles reduces chromatin interactions in active compartments

BACKGROUND: Nuclei of eukaryotes contain various higher-order chromatin architectures and nuclear bodies (NBs), which are critical for proper nuclear functions. Recent studies showed that active chromatin regions are associated with nuclear speckles (NSs), a type of NBs involved in RNA processing. H...

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Détails bibliographiques
Publié dans:Epigenetics Chromatin
Auteurs principaux: Hu, Shibin, Lv, Pin, Yan, Zixiang, Wen, Bo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636040/
https://ncbi.nlm.nih.gov/pubmed/31315647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-019-0289-2
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