Lycopene protects against myocardial ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening

BACKGROUND: Mitochondria permeability transition pore (MPTP) is an important therapeutic target for myocardial ischemia-reperfusion injury (MIRI). Lycopene (LP) is a potent antioxidant extracted from the mature fruits of plants and has been reported to protect against MIRI; however, its mechanism of...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Li, Xuying, Jia, Pengyu, Huang, Zijun, Liu, Shuang, Miao, Jiaxin, Guo, Yuxuan, Wu, Nan, Jia, Dalin
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635826/
https://ncbi.nlm.nih.gov/pubmed/31371925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S194753
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