A Novel Indolizine Derivative Induces Apoptosis Through the Mitochondria p53 Pathway in HepG2 Cells

Indolizine derivatives are a class of compounds with excellent biological activity. In this study, a series of indolizine derivatives, compound 1 (C1), compound 2 (C2), compound 3 (C3), and compound 4 (C4), were synthesized. 3-(4,5-dimethylthiazole)-2,5-diphenyltetraazolium bromide (MTT) assay was u...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Pharmacol
Päätekijät: Liu, Yushuang, Shao, Enxian, Zhang, Zhiyang, Yang, Daji, Li, Guanting, Cao, Hua, Huang, Hongliang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019
Aiheet:
Pharmacology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635656/
https://ncbi.nlm.nih.gov/pubmed/31354481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00762
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