Lycorine Induces Mitochondria-Dependent Apoptosis in Hepatoblastoma HepG2 Cells Through ROCK1 Activation

Lycorine, a naturally occurring compound extracted from the Amaryllidaceae plant family, has been reported to exhibit antitumor activity in various cancer cell types. In the present study, we investigated the molecular mechanisms underlying lycorine-induced apoptosis in hepatoblastoma HepG2 cells. W...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Liu, Wu-yi, Tang, Qin, Zhang, Qian, Hu, Chang-peng, Huang, Jing-bin, Sheng, Fang-fang, Liu, Ya-li, Zhou, Min, Lai, Wen-jing, Li, Guo-bing, Zhang, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589644/
https://ncbi.nlm.nih.gov/pubmed/31263414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00651
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