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Bile acids are potent inhibitors of rat P2X2 receptors

Extracellular adenosine triphosphate (ATP) regulates a broad variety of physiological functions in a number of tissues partly via ionotropic P2X receptors. Therefore, P2X receptors are promising targets for the development of therapeutically active molecules. Bile acids are cholesterol-derived amphi...

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Publicat a:Purinergic Signal
Autors principals: Schmidt, Axel, Joussen, Sylvia, Hausmann, Ralf, Gründer, Stefan, Wiemuth, Dominik
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635547/
https://ncbi.nlm.nih.gov/pubmed/31098843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-019-09657-2
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