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A Cytosolic Amphiphilic α-Helix Controls the Activity of the Bile Acid-sensitive Ion Channel (BASIC)

The bile acid-sensitive ion channel (BASIC) is a member of the degenerin/epithelial Na(+) channel (Deg/ENaC) family of ion channels. It is mainly found in bile duct epithelial cells, the intestinal tract, and the cerebellum and is activated by alterations of its membrane environment. Bile acids, one...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Schmidt, Axel, Löhrer, Daniel, Alsop, Richard J., Lenzig, Pia, Oslender-Bujotzek, Adrienne, Wirtz, Monika, Rheinstädter, Maikel C., Gründer, Stefan, Wiemuth, Dominik
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114408/
https://ncbi.nlm.nih.gov/pubmed/27679529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.756437
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