The ceramide moiety of disialoganglioside (GD3) is essential for GD3 recognition by the sialic acid–binding lectin SIGLEC7 on the cell surface

To analyze the binding specificity of a sialic acid–recognizing lectin, sialic acid-binding Ig-like lectin 7 (SIGLEC7), to disialyl gangliosides (GD3s), here we established GD3-expressing cells by introducing GD3 synthase (GD3S or ST8SIA1) cDNA into a colon cancer cell line, DLD-1, that expresses no...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Hashimoto, Noboru, Ito, Shizuka, Tsuchida, Akiko, Bhuiyan, Robiul H., Okajima, Tetsuya, Yamamoto, Akihito, Furukawa, Keiko, Ohmi, Yuhsuke, Furukawa, Koichi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Glycobiology and Extracellular Matrices
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635455/
https://ncbi.nlm.nih.gov/pubmed/31138648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007083
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