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Crystal structure of a Y-box binding protein 1 (YB-1)–RNA complex reveals key features and residues interacting with RNA

The Y-box binding protein 1 (YB-1) is a member of the cold shock domain (CSD) protein family and is recognized as an oncogenic factor in several solid tumors. By binding to RNA, YB-1 participates in several steps of posttranscriptional regulation of gene expression, including mRNA splicing, stabilit...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yang, Xiao-Juan, Zhu, Hong, Mu, Shi-Rong, Wei, Wen-Juan, Yuan, Xun, Wang, Meng, Liu, Yanchao, Hui, Jingyi, Huang, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635445/
https://ncbi.nlm.nih.gov/pubmed/31160337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007545
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