YB-1 binds to CAUC motifs and stimulates exon inclusion by enhancing the recruitment of U2AF to weak polypyrimidine tracts

The human Y box-binding protein-1 (YB-1) is a deoxyribonucleic acid (DNA)/ribonucleic acid (RNA)-binding protein with pleiotropic functions. Besides its roles in the regulation of transcription and translation, several recent studies indicate that YB-1 is a spliceosome-associated protein and is invo...

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Detalhes bibliográficos
Main Authors: Wei, Wen-Juan, Mu, Shi-Rong, Heiner, Monika, Fu, Xing, Cao, Li-Juan, Gong, Xiu-Feng, Bindereif, Albrecht, Hui, Jingyi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458536/
https://ncbi.nlm.nih.gov/pubmed/22730292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks579
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