Identification and Characterization of Genetic Determinants of Isoniazid and Rifampicin Resistance in Mycobacterium tuberculosis in Southern India

Drug-resistant tuberculosis (TB), one of the leading causes of death worldwide, arises mainly from spontaneous mutations in the genome of Mycobacterium tuberculosis. There is an urgent need to understand the mechanisms by which the mutations confer resistance in order to identify new drug targets an...

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Publicado no:Sci Rep
Main Authors: Munir, Asma, Kumar, Narender, Ramalingam, Suresh Babu, Tamilzhalagan, Sembulingam, Shanmugam, Siva Kumar, Palaniappan, Alangudi Natarajan, Nair, Dina, Priyadarshini, Padma, Natarajan, Mohan, Tripathy, Srikanth, Ranganathan, Uma Devi, Peacock, Sharon J., Parkhill, Julian, Blundell, Tom L., Malhotra, Sony
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635374/
https://ncbi.nlm.nih.gov/pubmed/31311987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46756-x
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