Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception

17β-Estradiol mediates the sensitivity to pain and is involved in sex differences in nociception. The widespread environmental disrupting chemical bisphenol A (BPA) has estrogenic activity, but its implications in pain are mostly unknown. Here we show that treatment of male mice with BPA (50 µg/kg/d...

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Published in:Sci Rep
Main Authors: Soriano, Sergi, Gil-Rivera, Minerva, Marroqui, Laura, Alonso-Magdalena, Paloma, Fuentes, Esther, Gustafsson, Jan-Ake, Nadal, Angel, Martinez-Pinna, Juan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635372/
https://ncbi.nlm.nih.gov/pubmed/31312012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46769-6
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