Prospective and comparative study of paroxysmal nocturnal hemoglobinuria patients treated or not by eculizumab: Focus on platelet extracellular vesicles

ABSTRACT: Thrombosis are severe complications of paroxysmal nocturnal hemoglobinuria (PNH), effectively reduced by eculizumab. Extracellular vesicles (EVs) may play a central role. The objective of this study was to assess the procoagulant activity of plasma isolated from PNH patients (treated or no...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Devalet, Bérangère, Wannez, Adeline, Bailly, Nicolas, Alpan, Lutfiye, Gheldof, Damien, Douxfils, Jonathan, Bihin, Benoît, Chatelain, Bernard, Dogné, Jean-Michel, Chatelain, Christian, Mullier, François
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635286/
https://ncbi.nlm.nih.gov/pubmed/31277120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000016164
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