Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice

Studies suggest that placental nutrient supply adapts according to fetal demands. However, signaling events underlying placental adaptations remain unknown. Here we demonstrate that phosphoinositide 3-kinase p110α in the fetus and the trophoblast interplay to regulate placental nutrient supply and f...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: López-Tello, Jorge, Pérez-García, Vicente, Khaira, Jaspreet, Kusinski, Laura C, Cooper, Wendy N, Andreani, Adam, Grant, Imogen, Fernández de Liger, Edurne, Lam, Brian YH, Hemberger, Myriam, Sandovici, Ionel, Constancia, Miguel, Sferruzzi-Perri, Amanda N
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
Assuntos:
Developmental Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634971/
https://ncbi.nlm.nih.gov/pubmed/31241463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45282
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