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Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice

Studies suggest that placental nutrient supply adapts according to fetal demands. However, signaling events underlying placental adaptations remain unknown. Here we demonstrate that phosphoinositide 3-kinase p110α in the fetus and the trophoblast interplay to regulate placental nutrient supply and f...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: López-Tello, Jorge, Pérez-García, Vicente, Khaira, Jaspreet, Kusinski, Laura C, Cooper, Wendy N, Andreani, Adam, Grant, Imogen, Fernández de Liger, Edurne, Lam, Brian YH, Hemberger, Myriam, Sandovici, Ionel, Constancia, Miguel, Sferruzzi-Perri, Amanda N
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634971/
https://ncbi.nlm.nih.gov/pubmed/31241463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45282
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