Tfap2a is a novel gatekeeper of nephron differentiation during kidney development

Renal functional units known as nephrons undergo patterning events during development that create a segmental array of cellular compartments with discrete physiological identities. Here, from a forward genetic screen using zebrafish, we report the discovery that transcription factor AP-2 alpha (tfap...

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Vydáno v:Development
Hlavní autoři: Chambers, Brooke E., Gerlach, Gary F., Clark, Eleanor G., Chen, Karen H., Levesque, Anna E., Leshchiner, Ignaty, Goessling, Wolfram, Wingert, Rebecca A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633607/
https://ncbi.nlm.nih.gov/pubmed/31160420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.172387
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