Authentically Phosphorylated α-Synuclein at Ser129 Accelerates Neurodegeneration in a Rat Model of Familial Parkinson's Disease

Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra (SN) and the appearance of fibrillar aggregates of insoluble α-synuclein (α-syn) called Lewy bodies (LBs). Approximately 90% of α-syn deposited in LBs is phosphorylated at serine 129 (Ser129)....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Sato, Hiroyasu, Arawaka, Shigeki, Hara, Susumu, Fukushima, Shingo, Koga, Kaori, Koyama, Shingo, Kato, Takeo
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2011
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633319/
https://ncbi.nlm.nih.gov/pubmed/22090514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3967-11.2011
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker