Authentically Phosphorylated α-Synuclein at Ser129 Accelerates Neurodegeneration in a Rat Model of Familial Parkinson's Disease

Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra (SN) and the appearance of fibrillar aggregates of insoluble α-synuclein (α-syn) called Lewy bodies (LBs). Approximately 90% of α-syn deposited in LBs is phosphorylated at serine 129 (Ser129)....

全面介紹

Na minha lista:
書目詳細資料
發表在:J Neurosci
Main Authors: Sato, Hiroyasu, Arawaka, Shigeki, Hara, Susumu, Fukushima, Shingo, Koga, Kaori, Koyama, Shingo, Kato, Takeo
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2011
主題:
Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633319/
https://ncbi.nlm.nih.gov/pubmed/22090514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3967-11.2011
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍