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Regulation of cyclic oligoadenylate synthesis by the Staphylococcus epidermidis Cas10-Csm complex

CRISPR-Cas systems are a class of adaptive immune systems in prokaryotes that use small CRISPR RNAs (crRNAs) in conjunction with CRISPR-associated (Cas) nucleases to recognize and degrade foreign nucleic acids. Recent studies have revealed that Type III CRISPR-Cas systems synthesize second messenger...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Nasef, Mohamed, Muffly, Mary C., Beckman, Andrew B., Rowe, Sebastian J., Walker, Forrest C., Hatoum-Aslan, Asma, Dunkle, Jack A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633199/
https://ncbi.nlm.nih.gov/pubmed/31076459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.070417.119
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