Molecular determinants for CRISPR RNA maturation in the Cas10–Csm complex and roles for non-Cas nucleases

CRISPR–Cas (Clustered regularly interspaced short palindromic repeats-CRISPR-associated proteins) is a prokaryotic immune system that destroys foreign nucleic acids in a sequence-specific manner using Cas nucleases guided by short RNAs (crRNAs). Staphylococcus epidermidis harbours a Type III-A CRISP...

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Udgivet i:Nucleic Acids Res
Main Authors: Walker, Forrest C., Chou-Zheng, Lucy, Dunkle, Jack A., Hatoum-Aslan, Asma
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389561/
https://ncbi.nlm.nih.gov/pubmed/28204542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw891
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