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Lyn Kinase Regulates Mesolimbic Dopamine Release: Implication for Alcohol Reward

We report here that the Src family tyrosine kinase Lyn negatively regulates the release of dopamine (DA) in the mesolimbic system, as well as the rewarding properties of alcohol. Specifically, we show that RNA interference-mediated knockdown of Lyn expression results in an increase in KCl-induced DA...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Gibb, Stuart L., Jeanblanc, Jerome, Barak, Segev, Yowell, Quinn V., Yaka, Rami, Ron, Dorit
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633047/
https://ncbi.nlm.nih.gov/pubmed/21307254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5540-10.2011
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