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Lyn Kinase Regulates Mesolimbic Dopamine Release: Implication for Alcohol Reward

We report here that the Src family tyrosine kinase Lyn negatively regulates the release of dopamine (DA) in the mesolimbic system, as well as the rewarding properties of alcohol. Specifically, we show that RNA interference-mediated knockdown of Lyn expression results in an increase in KCl-induced DA...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Gibb, Stuart L., Jeanblanc, Jerome, Barak, Segev, Yowell, Quinn V., Yaka, Rami, Ron, Dorit
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633047/
https://ncbi.nlm.nih.gov/pubmed/21307254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5540-10.2011
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