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Increased Neurotransmitter Release at the Neuromuscular Junction in a Mouse Model of Polyglutamine Disease

In Huntington's disease (HD), the expansion of polyglutamine (polyQ) repeats at the N terminus of the ubiquitous protein huntingtin (htt) leads to neurodegeneration in specific brain areas. Neurons degenerating in HD develop synaptic dysfunctions. However, it is unknown whether mutant htt impac...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Rozas, José L., Gómez-Sánchez, Leonardo, Tomás-Zapico, Cristina, Lucas, José J., Fernández-Chacón, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632945/
https://ncbi.nlm.nih.gov/pubmed/21248135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2011-10.2011
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