α5GABA(A) Receptor Activity Sets the Threshold for Long-Term Potentiation and Constrains Hippocampus-Dependent Memory

Synaptic plasticity, which is the neuronal substrate for many forms of hippocampus-dependent learning, is attenuated by GABA type A receptor (GABA(A)R)-mediated inhibition. The prevailing notion is that a synaptic or phasic form of GABAergic inhibition regulates synaptic plasticity; however, little...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Martin, Loren J., Zurek, Agnieszka A., MacDonald, John F., Roder, John C., Jackson, Michael F., Orser, Beverley A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632746/
https://ncbi.nlm.nih.gov/pubmed/20392949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4209-09.2010
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