Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p

Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is one of the major receptors expressed on the endothelium of arterial wall with a key role in endothelial dysfunction and the development of atherosclerosis. Recent evidence suggested that LOX-1 is upregulated under the condition of in...

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Udgivet i:PPAR Res
Main Authors: Xu, Lei, Zhao, Gang, Zhu, Hong, Wang, Shijun, Sun, Aijun, Zou, Yunzeng, Ge, Junbo
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632502/
https://ncbi.nlm.nih.gov/pubmed/31354796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2715176
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