Leptin Antagonizes Peroxisome Proliferator-Activated Receptor-γ Signaling in Growth Plate Chondrocytes

Leptin is an obesity-associated cytokine-like hormone encoded by the ob gene. Recent studies reveal that leptin promotes proliferation and differentiation of chondrocytes, suggesting a peripheral role of leptin in regulating growth plate function. Peroxisome proliferator-activated receptor-γ (PPARγ)...

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Bibliografiske detaljer
Main Authors: Wang, Lai, Shao, Yvonne Y., Ballock, R. Tracy
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458404/
https://ncbi.nlm.nih.gov/pubmed/23028384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/756198
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